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P53 by Sue Armstrong
£11.99
Available
Product Ref. (e.g. ISBN, SKU)
9781472910523
Published:
05 Nov 2015
Format:
Paperback
Number of pages:
287 pages
Dimensions:
198x129x19mm
Weight:
0.232kgs
Author:
All of us have lurking in our DNA a most remarkable gene. Its job is straightforward - to protect us from cancer. This gene - known simply as p53 - constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell makes a mistake in copying its DNA as part of its process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged and malfunctioning. This book reveals the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys and the breakthroughs.
The BMA Medical Book Award-shortlisted story of the search for p53 - the most important gene in medicine.
All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, summoning a repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control, p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or prevented from functioning normally.
This book tells the story of medical science's mission to unravel the mysteries of this crucial gene, and to get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, p53: The Gene that Cracked the Cancer Code reveals the fascination of the quest for scientific understanding, as well as the excitement of the chase for new cures - the hype, the enthusiasm, the lost opportunities, the blind alleys, and the breakthroughs. And as the long-anticipated revolution in cancer treatment tailored to individual patient's symptoms begins to take off at last, p53 remains at the cutting edge.
This tale of scientific discovery highlights the tremendous recent advances made in our understanding of cancer, a disease that affects more than one in three of us at some point in our lives.
About the Author: Sue Armstrong is a science writer and broadcaster based in Edinburgh. She has worked for a variety of media organisations, including New Scientist, and since the 1980s has undertaken regular assignments for the World Health Organization (WHO) and UNAIDS, writing about women's health issues and the AIDS pandemic, among many other topics, and reporting from the frontline in countries as diverse as Haiti, Papua New Guinea, Uganda, Thailand, Namibia and Serbia. Sue has been involved, as presenter, writer and researcher, in several major documentaries for BBC Radio 4; programmes have focused on the biology of ageing, and of drug addiction, alcoholism, obesity, AIDS, CJD, cancer and stress. Her books p53: The Gene that Cracked the Cancer Code and Borrowed Time: The Science of How and Why We Age are published by Bloomsbury Sigma.
| Number of pages | 287 |
|---|
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| First Item | 2 Items & Over | |
|---|---|---|
| UK | £3.75 | £5.00 |
| EU | £15.00 | £30.00 |
| USA & Canada | £30.00 | £50.00 |
| Rest of the World | £45.00 | £60.00 |
| Collect in Store | free | free |
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